GENETIC DIVERSITY OF IGHM AND IGHE IN THE LEPORIDS REVEALED DIFFERENT PATTERNS OF DIVERSITY IN THE TWO EUROPEAN RABBIT SUBSPECIES (O. CUNICULUS ALGIRUS AND O. C. CUNICULUS)

The European rabbit (Oryctolagus cuniculus) has been an important model for immunological studies but the study of its immunoglobulins (Ig) has been restricted to its unique IgA and IgG.Here, we studied the genetic diversity of IgM and IgE in several species of leporids and performed population genetics studies on European rabbit wild populations a

Abstract Background Epigenetic regulators are frequently mutated or aberrantly expressed in a Cleaning Kit variety of cancers, leading to altered transcription states that result in changes in cell identity, behavior, and response to therapy.Results To define alterations in epigenetic landscapes in breast cancers, we profiled the distributions of 8

Clear cell renal cell cancer (ccRCC) is a tumor of high malignancy, which can escape apoptosis.The tumor protein p53-inducible nuclear protein 2 (TP53INP2), known as an autophagy protein, is the essential part for autophagosome formation and sensitizes cells to apoptosis.Our study is aimed at exploring the role of TP53INP2 in ccRCC.We have identifi

Abstract In recent years, convolutional neural networks (CNNs) have made great achievements in the field of medical image segmentation, especially full convolutional neural networks based on U-shaped structures and skip connections.However, limited by the inherent Vacuums limitations of convolution, CNNs-based methods usually exhibit limitations in

Correlations are employed in modern physics to explain microscopic and macroscopic phenomena, like the fractional quantum Hall effect and the Mott insulator state in high Cleaning Kit temperature superconductors and ultracold atoms.Simultaneously probed neurons in the intact brain reveal correlations between their activity, an important measure to